The Kowloon Musjid and Islamic Centre was first established in 1896 by the Hong Kong Regiment. It was originally intended to serve the Indian Muslim troops of the British Army stationed at the nearby Whitfield Barracks, now the site of the adjacent Kowloon Park.
In the late 1970s, the building suffered structural issues due to the underground construction carried out for the Mass Transit Railway. With compensation provided by MTR Corporation and donations from the local Muslim community, a new Musjid was built and opened on 11 May 1984 on the present site at 105 Nathan Road to replace the old one.

Currently, the Musjid primarily serves Muslims from South Asia and Indonesia. Many of them also live in Tsim Sha Tsui, where ethnic minorities have settled. This also explains why it also plays an important role as a cultural site for non-Chinese Muslims in Hong Kong.
Vendors selling South Asian items at Chungking Mansions are close to the Kowloon Musjid (opposite the Musjid, across the road).
Kowloon Musjid is one of five main Musjids in Hong Kong. Located in Kowloon, in the Tsim Sha Tsui area at the intersection of Nathan Road and Haiphong Road, beside Kowloon Park, this Musjid is currently the largest in Hong Kong. The Musjid holds five prayers daily and is capable of accommodating up to 3,500 people.

The Musjid is located near exit A1 of Tsim Sha Tsui station (connected to East Tsim Sha Tsui station by underground walkways). It may be reached via the Tsuen Wan line or the Tuen Ma line (if you walk through the station to East Tsim Sha Tsui station).